Depression is one of the most common reasons patients pick up medical cannabis. Even in regions without medical cannabis, people have been using cannabis to self-medicate for depression for decades. It is well-known that the herb can temporarily improve mood, help you get a better night’s sleep, and cultivates a sense of positive well-being. But, are some strains better than others at defeating the blues? Here are the best cannabis strains for depression.
What are the best cannabis strains for depression?
Research on cannabis for depression has been inconclusive. While rodent studies have found that low doses of tetrahydrocannabinol (THC) may boost serotonin levels in rodents, the cannabinoid can have the opposite effect in high doses.
THC is the primary psychoactive in cannabis. Serotonin is a neurotransmitter that is often the target of popular antidepressant medications. Other preclinical research has found that another cannabis constituent, cannabidiol (CBD), has rapid-acting antidepressant effects in animal models.
While rodents certainly are not humans, this early research provides some insight into how the herb might one day be used in clinical practice. Thus far, it seems like low levels of THC and high levels of CBD might be a good place to start. Though, there is a still a lot to be said for personal preference.
To help you find the best buds, here are the best cannabis strains for depression:
Pennywise is an excellent choice for those experiencing depression. This strain typically contains a one-to-one ratio of THC to CBD, making it a balanced indica hybrid. With very mild psychoactive potency, this strain makes for a great daytime flower.
Considered an indica hybrid, the effects of this strain are relaxed and slightly sedative. However, they are more calming than sleepy. Those hoping for relief without a mind-warping high will appreciate this bud.
It is entirely possible that some people will respond better to CBD than to THC. Harlequin is a high-CBD strain with a 5:2 ratio of CBD to THC. This flower will not likely cause a psychoactive high. Instead, Harlequin inspires an easy, upbeat kind of mood.
Perfect for daytime relief, Harlequin is a powerful choice for the workday. While those accustomed to high-THC strains may find Harlequin a little lack-luster, this flower is a great way to warm up to cannabis.
3. Sour Tsunami
Sour Tsunami is another popular one-to-one strain. Like Pennywise, this flower does not cause a euphoric “high”. Rather, Sour Tsunami is laid back and calm, providing a gentle mood uplift that is unlikely to distort conscious thought. While psychoactive effects may be more noticeable in higher doses, Sour Tsu is a friendly daytime flower all around.
4. OG Kush
Sometimes a more powerful elevation is needed to find some relief from the blues. OG Kush is not only the most famous cannabis strain in history, but it also provides an incredible euphoric experience. This is a happy-go-lucky kind of flower, inspiring a pleasant mood and relaxed vibe.
Higher doses are recommended for those with cannabis experience. Otherwise, novices might experience some dizziness or paranoia. OG Kush is a high-THC strain and is recommended for the afternoon and evening.
5. Blue Dream
While OG Kush may be one of the most recognized strains in the world, Blue Dream is a close second. This high-THC strain is extremely popular both because it is easy to grow and also because it provides a very smooth and enjoyable hybrid experience.
Considered a safe daytime strain, Blue Dream is all smiles, jolliness, and relaxation. This bud is thought to have a creative vibe that might make it beneficial for working through mental roadblocks.
6. Granddaddy Purple
Insomnia is a common occurrence amongst those with depression. In times of need, a high-THC indica strain can come in handy. Granddaddy Purple is a sedative flower popular amongst medical cannabis patients with depression. This flower is recommended for nighttime consumption, and it provides a body-heavy yet mentally upbeat experience.
While insomnia may plague some with depression, chronic fatigue is also a problem. It’s not uncommon to hear that depression feels a bit like having the flu, complete with tiredness and physical aches and pains. Chocolope is a high-THC sativa popular among those seeking relief from depression.
This flower is energizing and can provide an intensely happy and uplifting experience. Those prone to THC-induced anxiety might want to steer clear of this flower, however. Chocolope has the tendency to cause anxiety. As with any high-THC, starting with small doses and working up when needed is recommended.
Note: The information in this article is intended for helpful and educational purposes and should not be used in place of medical advice or treatment.